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RNA interference therapy in cardiology: will new targets improve therapeutic goals?

Renata TJ Fazoli, Luciano F Drager, Roberto Kalil-Filho, Giuliano Generoso

Article Type

Review

Published

20 Aug 2024

This review highlights the historical timeline of the development of siRNA-based drugs, their clinical indications, potential side-effects and future perspectives.

Lipid-lowering interventions targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): an emerging chapter in lipid-lowering therapy

Constantine E Kosmas, Eddy DeJesus, Rosmery Morcelo, Frank Garcia, Peter D Montan, Eliscer Guzman

Article Type

Review

Published

22 Nov 2017

This review aims to present and discuss the current clinical and scientific data pertaining to lipid-lowering interventions targeting PCSK9.