The journey of remdesivir: from Ebola to COVID-19

Joe Pardo PharmD, Ashutosh M Shukla MD, Gajapathiraju Chamarthi MD, Asmita Gupte MD

Article Type

Review

Published

In this narrative review, an overview of Ebola and coronavirus outbreaks is provided as well as a summary of preclinical and clinical studies of remdesivir for Ebola and COVID-19.

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Pharmacological treatment of COVID-19: lights and shadows

Francesco Menzella MD, Mirella Biava Msc, Chiara Barbieri MD, Francesco Livrieri MD, Nicola Facciolongo MD

Article Type

Review

Published

The aim of this review is to explore COVID-19 treatment options and describe the potential benefits or disadvantages of their use in severe cases.

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Facing the COVID-19 outbreak in children with cancer

Antonio Ruggiero MD, Alberto Romano MD, Giorgio Attinà MD

Article Type

Editorial

Published

This editorial discusses the current COVID-19 outbreak and underlines that hygienic educational programs are fundamental and must be continued and implemented especially for immunosuppressed children.

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Chloroquine and hydroxychloroquine in the context of COVID-19

Ashutosh M Shukla MD, Lennox K Archibald MD, Aparna Wagle Shukla MD, Hiren J Mehta MD, Kartikeya Cherabuddi MD

Article Type

Review

Published

This review aims to present the available in vitro and in vivo data for the role of chloroquine/ hydroxychloroquine in COVID-19 and attempts to put them into perspective, especially in relation to the different risks/benefits particular to each patient who may require treatment.

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