hyaluronic acid Archives - Drugs in Context

Good scientific practice of using worldwide post-marketing surveillance data to ensure safety with HAALI BDDE cross-linked hyaluronic acid fillers

Hema Sundaram, Beatriz Molina, Editta Buttura da Prato, Gabriel Siquier-Dameto, Michela Zazzaron, Clara Cigni, Franco Grimolizzi

Article Type

Original Research

Published

18 Dec 2024

This article examines the real-world safety profile of aliaxin fillers fillers derived from worldwide post-marketing surveillance data

Three once-weekly intra-articular injections of Hylan G-F 20 significantly improve pain relief compared with placebo in patients with chronic idiopathic knee osteoarthritis: a single-centre, evaluator-blinded and patient-blinded, randomized controlled trial

Michael Langworthy, Peter Lascarides, Wilson Ngai, Kevin Steele, Yili Huang

Article Type

Original Research

Published

05 Apr 2024

This study was conducted to determine the efficacy and safety of three once-weekly injections of intra-articular Hylan G-F 20 in patients with chronic knee osteoarthritis over 26 weeks. It was hypothesized that Hylan G-F 20 would provide significant pain relief with no increased safety risk compared with IA saline (placebo).

Clinical and cost outcomes from different hyaluronic acid treatments in patients with knee osteoarthritis: evidence from a US health plan claims database

Vinod Dasa, Mitch DeKoven, Kainan Sun, Allan Scott, Sooyeol Lim

Article Type

Original Research

Published

23 Jun 2016

Intra-articular injection of hyaluronic acid (HA) for knee osteoarthritis (OA) effectively reduces pain and delays total knee replacement (TKR) surgery; however, little is known about relative differences in clinical and cost outcomes among different HA products. In this study, the authors conclude that analysis of administrative claims data provides real-world evidence that meaningful differences exist among some HA products in disease-specific cost and time to knee replacement surgery.