Understanding treatment goals and their application in clinical trial design for patients with Alzheimer disease and caregivers

David Gómez-Ulloa, M Chris Runken, Wilton I Rodriguez, Basilio Hernández, Montserrat Chivite, E Anne Davis, Paul Nisbet

Article Type

Original Research

Published

The goal of the present study was to survey patients with AD and caregivers to establish what they considered to be the most important treatment goals, thereby providing data for the systematic incorporation of these goals into Alzheimer disease clinical trials.

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Propranolol for the management of behavioural and psychological symptoms of dementia

Rajesh R Tampi, Deena J Tampi, Syeda Arshiya Farheen, Sochima I Ochije, Pallavi Joshi

Article Type

Review

Published

There is some evidence that propranolol may benefit individuals with behavioural and psychological symptoms of dementia (BPSD). This article discusses three case series that assessed the use of propranolol for the management of BPSD. From these studies, it appears that propranolol improves BPSD and is well tolerated. In clinical practice, the routine use of propranolol among people with BPSD cannot be recommended at this time given the limited data. However, propranolol can be trialled among individuals with BPSD when symptoms have not responded adequately to other medications.

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