Drugs for paediatric hyperinflammatory syndromes

Kam Lun Hon, Alexander KC Leung, Wing Hang Leung, Karen Ka Yan Leung, Kai Ning Cheong, Pamela PW Lee

Article Type

Review

Published

This paper provides an updated narrative review on the pathophysiology, manifestations and management approaches for common hyperinflammatory syndromes.

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Real-world use of inhaled nitric oxide therapy in patients with COVID-19 and mild-to-moderate acute respiratory distress syndrome

Steven H Abman, Nicholas R Fox, M Ibrahim Malik, Sneha S Kelkar, Shelby L Corman, Sanika Rege, Jenna Bhaloo, Rachel Shah, Ren-Jay Shei, Dana Saporito, Nisreen Shamseddine, Erik DeBoer, George J Wan, on behalf of the NOTICE Study Investigators

Article Type

Original Research

Published

This article aims to describe real-world inhaled nitric oxide use and outcomes in patients with COVID-19 with mild-to-moderate acute respiratory distress syndrome in the United States.

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Open-label use of an aliphatic polyamine immunomodulator in patients hospitalized with COVID-19

Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Luydmila Yu Akhieva, Elena V Kuntsevich, Anastasia A Troshina, Elena I Kvasova, Anton A Tikhonov, Nadezhda F Khomyakova, Francisco Harrison, Jean-François Rossi, Timothy C Hardman

Article Type

Original Research

Published

This study evaluated the safety and efficacy of azoximer bromide when used in combination with standard of care treatment in patients hospitalized with COVID-19.

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Combating the opioid epidemic in the United States

A Simon Pickard, Todd A Lee

Article Type

Editorial

Published

This editorial discusses the series of papers that feature initiatives to mitigate the opioid epidemic in the United States, and challenges encountered during the Covid-19 pandemic.

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