Heart failure is probably the area of cardiology that has grown the most in recent years with a likely turning point being, for example, the publication of results of the PARADIGM-HF study (Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure) in 2014, which is the largest study conducted to date in heart failure (8842 patients). For example, in the 6 years from September 2006, to September 2014, PubMed registered a total of 72,694 results tagged with the keyword “heart failure”, while in the following 6 years, from September 2014, to September 2022, the number increased to 120,102 documents. The objective of this series is to provide a comprehensive review covering different topics of interest that belong within the broad spectrum of heart failure. I hope that readers find the articles presented here interesting and useful, and that they also enjoy reading them.
Review
This article reviews an updated therapeutic algorithm for heart failure with reduced ejection fraction (HFrEF) with a special focus on the therapeutic value of adding an mineralocorticoid receptor antagonist, changing an angiotensin-converting enzyme inhibitor/angiotensin receptor blocker for an angiotensin
II receptor-neprilysin inhibitor and incorporating an sodium–glucose cotransporter 2 inhibitor in patients with HFrEF.
Review
This review provides comprehensive information about vericiguat in terms of its differential mechanism of action and clinical data particularly focused on the VICTORIA trial.
Review
This article provides an overview of the main pathophysiological characteristics of heart failure with preserved ejection fraction (HFpEF), the considered diverse biological effects of sodium–glucose cotransporter 2 inhibitors (SGLT2i) in this context and the supporting clinical evidence of SGLT2i in patients with HFpEF with a focus on the EMPEROR-Preserved and DELIVER trials.
Review
The author present a narrative review that comprehensively addresses the pathophysiology, clinical manifestations, and therapeutic management of tachycardia-induced cardiomyopathy.
Review
This article reviews point-of-care ultrasound (POCUS) application in the emergency department or the intensive care unit, focused on severely compromised patients with cardiogenic shock with an emergent bedside assessment.
Review
The authors present a literature review which provides simple information, evidence-based indications, and a practical approach for cardiologists who may encounter acutely ill adult patients that may be extracorporeal membrane oxygenation candidates.
