Articles

One-year prevalence, comorbidities and cost of cachexia-related inpatient admissions in the USA

Susan T Arthur, Joshua M Noone, Bryce A Van Doren, Debosoree Roy, Christopher M Blanchette

Article Type

Original Research

Published

Cachexia is a condition characterized as a loss in body mass or metabolic dysfunction and it is associated with several prevalent chronic health conditions including many cancers, COPD, HIV, and kidney disease. Currently there is little research into cachexia and the objective of this article is to characterize cachexia patients, their healthcare utilisation, and associated hospitalization costs.

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Empagliflozin: a new sodium-glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes

Joshua J Neumiller

Article Type

Review

Published

Type 2 diabetes is increasing in prevalence worldwide, and hyperglycemia is often poorly controlled despite a number of therapeutic options.

Unlike previously available agents, sodium-glucose co-transporter 2 inhibitors offer an insulin-independent mechanism for improving blood glucose levels, since they promote urinary glucose excretion by inhibiting glucose reabsorption in the kidney.

In this article, the author discusses empagliflozin and based on available data, it appears that this drug may be a useful option in a range of patients; however, clinical decisions will be better informed by the results of ongoing studies, in particular, a large cardiovascular outcome study (EMPA-REG OUTCOME™).

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Study protocol for a randomized, controlled trial comparing the efficacy of two educational interventions to improve inhalation techniques in patients with chronic obstructive pulmonary disease (COPD): TIEPOC Study.

José Leiva-Fernández, Francisca Leiva-Fernández, Rubén L Vázquez-Alarcón, Antonio García-Ruiz, Daniel Prados-Torres, Pilar Barnestein-Fonseca

Article Type

Case Report

Published

Up to 75% of patients with COPD do not use a correct inhaler technique. In this article, the authors provide details of a study protocol for a randomized controlled trial to test the efficacy of two educational interventions aimed at improving inhalation techniques in a cohort of patients in southern Spain.

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Tardive dyskinesia in patients treated with atypical antipsychotics: case series and brief review of etiologic and treatment considerations

Jungjin Kim, Eric MacMaster, Thomas L Schwartz

Article Type

Case Report

Published

Tardive dyskinesia (TD) can be a disfiguring side-effect of antipsychotic medications. In this article the authors review the risk of TD, the potential etiologic mechanisms and present some interesting cases of patients taking atypical antipsychotics who developed TD.

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