Articles - Page 70 of 96 - Drugs in Context

Effectiveness and safety of mepolizumab in severe refractory eosinophilic asthma: results in clinical practice

Olalla Montero-Pérez PharmD, María Beatriz Contreras-Rey PharmD, Ernesto Sánchez-Gómez PhD

Article Type

Original Research

Published

27 May 2019

This article analyses the effectiveness, clinical outcomes, and safety of mepolizumab in clinical practice.

Brodalumab in psoriasis: evidence to date and clinical potential

Amy C Foulkes BMedSci (Hons), BMBS, MRCP (Derm), PhD, Richard B Warren BSc (Hons), MBChB (Hons), MRCP, PhD

Article Type

Review

Published

17 Apr 2019

This article reviews brodalumab’s place in the expanding armamentarium of cytokine-directed therapies for patients with severe psoriasis.

Efficacy and steroid-sparing effect of benralizumab: has it an advantage over its competitors?

Francesco Menzella MD, Mirella Biava Msc, Diego Bagnasco MD, PhD, Carla Galeone Msc, Anna Simonazzi MD, Patrizia Ruggiero Msc, Nicola Facciolongo MD

Article Type

Review

Published

15 Apr 2019

This article is an indirect comparison among literature data, especially between OCS reduction studies (ZONDA-SIRIUS) and pivotal studies (SIROCCO-MENSA), evaluating whether the clinical efficacy and the steroid-sparing effect of benralizumab may represent an advantage over other compounds. This data could help the clinician in the decision process of treatment choice, within the different available therapeutic options for eosinophilic refractory severe asthma.

New developments in ulcerative colitis: latest evidence on management, treatment, and maintenance

Kartikeya Tripathi MD, Joseph D Feuerstein MD

Article Type

Review

Published

22 Apr 2019

Ulcerative colitis is a chronic idiopathic inflammatory disorder that involves any part of the colon. The authors review the latest evidence on management, treatment, and maintenance.

Second-line treatment options in hepatocellular carcinoma

Donatella Marino MD, Clizia Zichi MD, Marco Audisio MD, Elisa Sperti MD, Massimo Di Maio MD

Article Type

Review

Published

10 Apr 2019

This review discusses the evidence on second-line options for hepatocellular carcinoma, focusing on the latest results that are currently refining the treatment scenario.