Articles

Overcoming hurdles: measurement of health-related outcomes associated with national level medicines usage in Ireland

Gary L O’Brien BPharm, MPharm, Muireann McAlister BSc Pharmacy, Stephen Byrne BSc Pharmacy, PhD, James Gallagher BPharm, MPharm, PhD

Article Type

Editorial

Published

This editorial provides an overview of the evolving healthcare landscape surrounding medicine usage estimation and valuation in Ireland and offers recommendations on how improved methods of measuring health-related outcomes may help ameliorate efficiencies and the sustainability of a healthcare system.

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Pharmacological treatment of COVID-19: lights and shadows

Francesco Menzella MD, Mirella Biava Msc, Chiara Barbieri MD, Francesco Livrieri MD, Nicola Facciolongo MD

Article Type

Review

Published

The aim of this review is to explore COVID-19 treatment options and describe the potential benefits or disadvantages of their use in severe cases.

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Rectal neuroendocrine carcinoma: case report of a rare entity and perspective review of promising agents

Gabriela Antelo MD, Cinta Hierro MD, MSc, Juan Pablo Fernández MD, Eduardo Baena MD, Cristina Bugés MD, Laura Layos MD, José Luis Manzano MD, Mónica Caro MD, Ricard Mesia MD, PhD

Article Type

Review

Published

This article discusses the current management of this rare entity and provide an overview of the most relevant molecular findings, whilst illustrating the potential value that prescreening panels can offer, searching for actionable targets (MSI/dMMR, PD-L1, BRAFv600E) to guide therapy with promising agents that could fill a void in this disease.

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Facing the COVID-19 outbreak in children with cancer

Antonio Ruggiero MD, Alberto Romano MD, Giorgio Attinà MD

Article Type

Editorial

Published

This editorial discusses the current COVID-19 outbreak and underlines that hygienic educational programs are fundamental and must be continued and implemented especially for immunosuppressed children.

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