Articles

Non-small-cell lung cancer: how to manage RET-positive disease

Elisa Andrini, Mirta Mosca, Linda Galvani, Francesca Sperandi, Biagio Ricciuti, Giulio Metro, Giuseppe Lamberti

Article Type

Review

Published

This article reviews the biology, clinicopathological characteristics, targeted therapies and mechanisms of resistance of advanced non-small-cell lung cancer harbouring RET fusions to provide treatment guidance for these patients.

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Advanced non-small-cell lung cancer: how to manage non-oncogene disease

Andrea De Giglio, Alessandro Di Federico, Chiara Deiana, Biagio Ricciuti, Marta Brambilla, Giulio Metro

Article Type

Review

Published

This article provides a review of the current treatment approaches to advanced non-small-cell lung cancer in patients without molecular driver alterations, with an additional focus on special populations, concomitant medications, and other considerations that might be useful for daily clinical practice.

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