Articles

Relationship between breakthrough cancer pain, background cancer pain and analgesic treatment – case series and review of the literature

Chrysanthi Batistaki, Michal Graczyk, Marcin Janecki, Agata Anna Lewandowska, Rita Moutinho, Kiriaki Vagdatli

Article Type

Review

Published

The aim of this paper is to provide healthcare professionals involved in cancer pain management with a review of the relevant literature on the relationship between background cancer pain and breakthrough cancer
pain.

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Deferiprone, an iron chelator, alleviates platelet hyperactivity in patients with β-thalassaemia/HbE

Ngan Thi Tran, Pranee Sutcharitchan, Jindaporn Janprasit, Ponlapat Rojnuckarin, Noppawan Phumala Morales, Rataya Luechapudiporn

Article Type

Original Research

Published

This study was designed to evaluate the antiplatelet effect of deferiprone in patients with transfusion-dependent β-thalassaemia/Hb E at the dose of iron-chelation therapy. The results may provide a mechanistic insight in antiplatelet effects and support the benefit of deferiprone in the prevention of thrombotic events in β-thalassaemia.

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Propranolol for the management of behavioural and psychological symptoms of dementia

Rajesh R Tampi, Deena J Tampi, Syeda Arshiya Farheen, Sochima I Ochije, Pallavi Joshi

Article Type

Review

Published

There is some evidence that propranolol may benefit individuals with behavioural and psychological symptoms of dementia (BPSD). This article discusses three case series that assessed the use of propranolol for the management of BPSD. From these studies, it appears that propranolol improves BPSD and is well tolerated. In clinical practice, the routine use of propranolol among people with BPSD cannot be recommended at this time given the limited data. However, propranolol can be trialled among individuals with BPSD when symptoms have not responded adequately to other medications.

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How to manage KRAS G12C-mutated advanced non-small-cell lung cancer

Biagio Ricciuti, Alessia Mira, Elisa Andrini, Pietro Scaparone, Sandra Vietti Michelina, Federica Pecci, Luca Cantini, Andrea De Giglio, Giuseppe Lamberti, Chiara Ambrogio, Giulio Metro

Article Type

Review

Published

The authors review the current treatment landscape for patients with advanced non-small-cell lung cancers harbouring a KRAS G12C mutation, including PD-(L) 1-based therapies and direct KRAS inhibitors as well as sequential treatment options.

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Tinea versicolor: an updated review

Alexander KC Leung, Benjamin Barankin, Joseph M Lam, Kin Fon Leong, Kam Lun Hon

Article Type

Review

Published

This review aims to familiarize physicians with the clinical features, diagnosis and management of tinea versicolor.

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