Severe hypereosinophilia in a patient treated with dupilumab and shift to mepolizumab: the importance of multidisciplinary management. A case report and literature review

Sara Munari, Giulia Ciotti, Walter Cestaro, Lorenzo Corsi, Silvia Tonin, Andrea Ballarin, Ariel Floriani, Cristina Dartora, Annamaria Bosi, Matteo Tacconi, Francesco Gialdini, Michele Gottardi, Francesco Menzella

Article Type

Review

Published

This article describes a case of severe hypereosinophilia in a patient with chronic rhinosinusitis with nasal polyps and asthma treated with dupilumab and a subsequent therapeutic shift to mepolizumab that led to maintenance of symptom control and concomitant normalization of blood eosinophil count.

Read more

Bilastine for the treatment of allergic rhinoconjunctivitis and urticaria: results from an international Delphi study

Giorgio Walter Canonica, Piotr Kuna, Marcus Maurer, Ralph Mösges, Zoltan Novak, Nikolaus Papadopoulos, Pablo Rodriguez del Rio, the Delphi Study Group

Article Type

Original Research

Published

This study analyses available evidence supporting the use of bilastine amongst second-generation antihistamines for the symptomatic treatment of allergic rhinitis and urticaria in adults and children.

Read more

Sleep-related breathing disorder (central sleep apnoea) improved coincidentally by medical therapy with fumarates (dimethyl fumarate)

Abdulmajeed M Albadi, Mana M Alshahrani, Riyad O Allehebi

Article Type

Case Report

Published

In this article, the authors describe a case study of a 31-year-old woman known to have multiple sclerosis and concomitant severe central sleep apnoea (CSA). She received the medication dimethyl fumarate for the treatment of multiple sclerosis, and her CSA significantly improved to mild CSA after the treatment.

Read more

Ingredients of Vicks VapoRub inhibit rhinovirus-induced ATP release

Rebecca J Stinson, Alyn H Morice, Basir Ahmad, Laura R Sadofsky

Article Type

Original Research

Published

This article suggests that some Vicks VapoRub ingredients may reduce symptoms associated with upper respiratory tract infection by modulating specific TRP receptors and by reducing RV16-induced ATP release.

Read more

Register for alerts

I would like to be contacted by Drugs in Context when new articles are posted.