Management of pre-renal transplant secondary hyperparathyroidism: parathyroidectomy versus cinacalcet

Muhammed Ahmed Elhadedy, Ghada El-Kannishy, Ayman F Refaie, Hussein A Sheashaa, Ahmed Halawa

Article Type

Original Research

Published

This research compares the effectiveness of parathyroidectomy versus cinacalcet for the treatment of secondary hyperparathyroidism, assessing the short-term and long-term impact on renal allograft survival and the chronic
kidney disease and mineral bone disorder profile following transplantation.

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Hypophosphataemia, fibroblast growth factor 23 and third-generation intravenous iron compounds: a narrative review

Xenophon Kassianides BSc (Hons), MBBS, MRCP(UK), Sunil Bhandari MBChB, MRCP, FRCP, PhD, M Clin Edu, FHEA

Article Type

Review

Published

This review focues on the links between iron and phosphate metabolism, the most recent comparative studies between third-generation i.v. iron compounds, the important role of fibroblast growth factor 23 (FGF23), and the impact of hypophosphataemia on the patient. This review also presents an algorithm that can be used in patients requiring i.v. iron in anticipation of potential hypophosphataemia.

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Cinacalcet adherence in dialysis patients with secondary hyperparathyroidism in Lombardy Region: clinical implications and costs

Alessandro Roggeri BSc, Ferruccio Conte MD, Carlotta Rossi MSc, Mario Cozzolino MD, PhD, Carlo Zocchetti MSc, Daniela Paola Roggeri MSc

Article Type

Original Research

Published

This retrospective observational study evaluated, in dialysis patients with SHPT, the impact of different levels of adherence to cinacalcet therapy on hospitalisations and direct healthcare costs charged to the Lombardy Regional Health Service (Italy).

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