Use of immunomodulatory therapy as part of comprehensive treatment of non-severe community-acquired pneumonia and its long-term results

Mikhail P Kostinov, Vilia V Gainitdinova, Svetlana V Kazharova, Anna E Vlasenko, Vflentina B Polishchuk, Kirill V Mashilov

Article Type

Original Research

Published

This work aims to study the effectiveness of two different types of immunomodulators for the treatment of non-severe community-acquired pneumonia and assesses the long-term effects of the treatment conducted.

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Changes in nasal, pharyngeal and salivary secretory IgA levels in patients with COVID-19 and the possibility of correction of their secretion using combined intranasal and oral administration of a pharmaceutical containing antigens of opportunistic microorganisms

Mikhail Kostinov, Oksana Svitich, Alexander Chuchalin, Natalya Abramova, Valery Osiptsov, Ekaterina Khromova, Dmitry Pakhomov, Vitaly Tatevosov, Anna Vlasenko, Vilia Gainitdinova, Kirill Mashilov, Nadezhda Kryukova, Irina Baranova, Anton Kostinov

Article Type

Original Research

Published

This article aims to assess the secretion of SIgA in the nasal and pharyngeal compartments and saliva of patients with COVID-19 and to investigate the possibility and efficiency of correction of their secretion using combined intranasal and oral administration of a pharmaceutical containing antigens of opportunistic microorganisms.

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Drugs for paediatric hyperinflammatory syndromes

Kam Lun Hon, Alexander KC Leung, Wing Hang Leung, Karen Ka Yan Leung, Kai Ning Cheong, Pamela PW Lee

Article Type

Review

Published

This paper provides an updated narrative review on the pathophysiology, manifestations and management approaches for common hyperinflammatory syndromes.

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Open-label use of an aliphatic polyamine immunomodulator in patients hospitalized with COVID-19

Sergey V Efimov, Natallia V Matsiyeuskaya, Olga V Boytsova, Luydmila Yu Akhieva, Elena V Kuntsevich, Anastasia A Troshina, Elena I Kvasova, Anton A Tikhonov, Nadezhda F Khomyakova, Francisco Harrison, Jean-François Rossi, Timothy C Hardman

Article Type

Original Research

Published

This study evaluated the safety and efficacy of azoximer bromide when used in combination with standard of care treatment in patients hospitalized with COVID-19.

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