Precautions in the management of opioid agonist therapy: from target population characteristics to new formulations and post-marketing monitoring – a focus on the Italian system

Guido Mannaioni, Fabio Lugoboni

Article Type

Review

Published

This articles aims is to provide useful information and insights for the management of opioid agonist therapy by providing an overview that ranges from the characteristics of opioid use disorder patients to the macroscopic phenomena of social-health significance on a national scale, with a particular focus on the Italian territory.

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Individuals at risk for severe COVID-19 in whom ritonavir-containing therapies are contraindicated or may lead to interactions with concomitant medications: a retrospective analysis of German health insurance claims data

Christoph Lübbert, Igor Dykukha, Jann-Patrick Pelz, Helen Yearley, Wolfgang Junker, Nina Gruber, Sibyll Escher, Katrin Biereth, Sima Melnik, Julia Puschmann

Article Type

Review

Published

This article aimed to assess the prevalence of individuals with one or more risk factors for severe COVID-19 along with contraindications and potential drug–drug interactions due to ritonavir-containing COVID-19 therapy.

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The future of clinical trials and drug development: 2050

Timothy C Hardman, Rob Aitchison, Richard Scaife, Jean Edwards, Gill Slater, on behalf of the Committee of the Pharmaceutical Contract Management Group

Article Type

Commentary

Published

This article discusses a workshop held at the 18th Annual Conference of the Pharmaceutical Contract Management Group (PCMG) in Krakow on 9th September 2022, which asked over 200 delegates what the clinical trial landscape would look like in 2050.

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A real-world evidence study evaluating consumer experience of Supradyn Recharge or Supradyn Magnesium and Potassium during demanding periods

Barbara Moroni, Veronika Óvári, Cristina Nicastro, Raffaella de Salvo, Andreas Ehret

Article Type

Original Research

Published

This article reports findings on consumption behaviour, reason for intake and frequency of intake as well as consumer experience, satisfaction and characteristics of Supradyn Recharge or Supradyn Magnesium+Potassium.

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Drug costs in context: assessing drug costs in cost-of-illness analyses

T Joseph Mattingly II, Shannon Weathers

Article Type

Commentary

Published

This article aims to provide contextual information for a general audience interested in conducting or evaluating cost-of-illness studies that may include drug costs and to describe key factors to consider when reviewing drug costs in the peer-reviewed literature.

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