Drug therapy for double-hit lymphoma

Vania Phuoc MD, Jose Sandoval-Sus MD, Julio C Chavez MD, MS

Article Type

Review

Published

This review discusses the role of hematopoietic stem cell transplantation (HCT) and chimeric antigen receptor (CAR) T-cell therapy in DHL, as well as the role of potential novel agents such as BCL2 inhibitors, checkpoint inhibitors, bromodomain and extraterminal (BET) family inhibitors, Pi3K inhibitors, and others.

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Neonatal pharmacology and clinical implications

Antonio Ruggiero MD, Anna Ariano MD, Silvia Triarico MD, Michele Antonio Capozza MD, Pietro Ferrara MD, Giorgio Attinà MD

Article Type

Review

Published

This review article analyses the main pharmacokinetic aspects (ADME) that exist during the neonatal period and offers a description of the physiological background for variability in pharmacological dosing.

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Venetoclax: evidence to date and clinical potential

Luis Miguel Juárez-Salcedo MD, Viraj Desai BA, Samir Dalia MD

Article Type

Review

Published

Thsi review article describes the mechanism of action that stands behind the efficacy of venetoclax and provides a summary of available results from clinical trials.

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