Article Type
Review
Published
This review discusses the evidence on second-line options for hepatocellular carcinoma, focusing on the latest results that are currently refining the treatment scenario.
Category: Gastroenterology
Article Type
Review
Published
Over the past ten years, sorafenib has been the only systemic agent approved for first-line treatment of patients with unresectable hepatocellular carcinoma (HCC) and in a second-line setting, most investigational drugs have failed to provide better survival outcomes than placebo. However, in 2016, data from the RESORCE trial, a phase 3 study evaluating regorafenib in HCC patients who experience disease progression after first-line treatment with sorafenib, have shown a 2.8-month median survival benefit over placebo (10.6 versus 7.8 months).
Article Type
Review
Published
This article summarizes the latest evidence and clinical implication in treatment of diverticular disease focusing either on the treatment of diverticulosis, symptomatic uncomplicated diverticular disease and acute diverticulitis together with the primary and secondary prevention of diverticulitis.
Article Type
Original Research
Published
This article aims to assess the epidemiology of ulcerative colitis at hospital gastroenterology units and the use of hospital resources for the management of ulcerative colitis in Spain.
Article Type
Case Report
Published
The authors report a case of primary prostate and lung tumors associated with gastric and small bowel GISTs, unrelated to any known hereditary syndrome.
