Real-life effectiveness of FLOT in resectable gastric cancer: existing challenges

Francesco Serra, Federica Valerio, Paolo Pedrazzoli, Jacopo Viganò, Riccardo Caccialanza, Daniela Cicognini, Anna Pagani, Salvatore Corallo

Article Type

Original Research

Published

This article aims to demonstrate the real-life effectiveness of the fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT) regimen by comparing it with traditional chemotherapy regimens and aims to discover its strengths and weaknesses.

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Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres

David Young, Sohail Rahmany, Deborah Taylor, Emma Davis, Michael Colwill, Sonia Kalyanji Mehta, Roisin Campbell, Karl Hazel, Karishma Sethi-Arora, Susan Ritchie, Ashley I Heinson, Helen Moyses, Keith Bodger, Emma Johnston, Lucy Hicks, Anjan Dhar, Jimmy Limdi, Rachel Cooney, John Paul Seenan, Kamal Patel, Alissa Walsh, Fraser Cummings

Article Type

Original Research

Published

This article reports the real-world
experience of 286 patients with ulcerative colitis treated with filgotinib as part of their routine clinical care in 9 UK centres.

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Review and expert opinion on MAFLD, oxidative stress and multifunctional management

Francesco Angelico, Diana Alcantara-Payawal, Rafiz Abdul Rani, Norlaila Mustafa, Nuntakorn Thongtang, Roongruedee Chaiteerakij, Chalermrat Bunchorntavakul, Apichard Sukonthasarn

Article Type

Review

Published

This review summarizes the current knowledge about metabolic-associated fatty-liver disease (MAFLD) and reports the opinion of a group of experts on the increasing prevalence and burden of the disease in the southeast Asia region, the current journey of patients with MAFLD in developing countries, the role of oxidative stress and antioxidant treatment, and the importance of a multidisciplinary approach for early diagnosis and disease management.

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