Cardiology and cardiovascular disease Archives

Role of aspirin in the primary prevention of cardiovascular disease in patients with hyperlipoproteinaemia(a)

Eleni Giannopoulou, Loukianos S Rallidis, Donatos Tsamoulis, Maria Gianniou, Constantine E Kosmas

Article Type

Review

Published

31 Dec 2024

This comprehensive review aims to provide readers with the current data on the use of aspirin as a primary prevention tool for atherosclerotic cardiovascular disease in patients with elevated lipoprotein(a) levels.

Inclisiran for the treatment of hypercholesterolaemia

Joel C Marrs, Sarah L Anderson

Article Type

Review

Published

28 Nov 2024

This narrative review presents and examines current evidence regarding the use of inclisiran for the treatment of hyperlipidaemia and its potential role to reduce cardiovascular events.

RNA interference therapy in cardiology: will new targets improve therapeutic goals?

Renata TJ Fazoli, Luciano F Drager, Roberto Kalil-Filho, Giuliano Generoso

Article Type

Review

Published

20 Aug 2024

This review highlights the historical timeline of the development of siRNA-based drugs, their clinical indications, potential side-effects and future perspectives.

Risk of gastrointestinal bleeding in Asian patients receiving oral anticoagulants for stroke prevention in atrial fibrillation

Alejandro Bimbo Diaz, Jeremy Chow, Fan Kee Hoo, Gary Lee Chin Keong, Narayanaswamy Venketasubramanian, Nannette Rey, Gregorio Rogelio, Radhika Mehta

Article Type

Meeting Report

Published

13 Aug 2024

The Menarini Asia Pacific Advancing Patient care with EdoXaban (APEX) 2023 Expert Meeting convened in Kuala Lumpur, Malaysia, and provided a forum for experts to explore the occurrence of gastrointestinal bleeding linked to non-vitamin K antagonist oral anticoagulants in Asian clinical practice for stroke prevention in atrial fibrillation. This report amalgamates insights from two segments of the meeting.

A UK multicentre audit of the management of patients with primary hypercholesterolaemia or mixed dyslipidaemia with bempedoic acid against published lipid-lowering treatment targets

Sudarshan Ramachandran, Amro Maarouf, Karen Mitchell, Tony Avades, Peter Smith, Lee Boulton, Jennifer Kelly, Nitasha Vekaria, Elizabeth Hughes

Article Type

Original Research

Published

08 Aug 2024

This retrospective multicentre audit aimed to evaluate the achievement of lipid-lowering targets with bempedoic acid in UK patients based on recommendations in the Joint British Societies (JBS) guidelines for the prevention of cardiovascular disease.